• React Health G3X CPAP machine with black front panel, digital display and control dial, plus a clear water chamber on the right.
  • React Health G3X Auto CPAP machine with a black design digital display control dial home button and clear humidifier chamber beside it
  • React Health G3X Auto CPAP machine kit with carrying case, humidifier chamber, tubing, power cords, and user manuals displayed together
  • React Health G3X Auto CPAP machine with humidifier beside a sleeping patient wearing a nasal mask in a comfortable bedroom setting
  • React Health G3X Auto CPAP machine with a black display and clear humidifier chamber on a wooden bedside table beside a plant and bed
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React Health SKU: G4600

G3X Auto CPAP Machine

$873.00
$873.00

  • Free Expedited Shipping ⓘ
  • 60 Days to Return ⓘ You can return any new and unopened item within 60-nights from date of delivery for a full refund to your original payment method. Expedited shipping costs are not eligible for refund. Used or opened returned items will be refunded to a Lofta Store Credit (exceptions apply). Learn more
  • Best Price Guaranteed ⓘ Find a better price somewhere else? Give us a call at 800-698-8000 and we will not only match the price but will best it by 10% of the difference. Learn more
  • Expert customer support
Earn Rest Rewards Points with Every Purchase
FSA/HSA Eligible ⓘ
The React Health G3 X is the first standard-size CPAP machine available in the U.S. engineered completely without polyurethane sound-abatement foam. Using a unique honeycomb design, it delivers dependable, quiet therapy (under 28 dBA) with no degrading materials, nothing to off-gas, and no foam particles between you and your therapeutic air — giving you clean airflow and long-term peace of mind.

Works With Any Mask
The G3 X connects to any standard 22mm CPAP mask — nasal, nasal pillow, or full face — regardless of brand, so you can keep the mask you already love or choose freely from every major manufacturer. There is no proprietary lock-in and no adapter to buy; simply plug in a standard 22mm tube and your existing mask is ready to go. The only exception is the ResMed AirMini, which uses proprietary tubing and requires a separately sold adapter.

'Smart A' Custom Pressure Response

Exclusive Smart A technology personalizes your therapy by adapting the auto algorithm over a rolling five-session window. It reviews data from your last five successful sessions (at least 4 hours with leak under 90 L/min) and automatically fine-tunes your Auto Min and Auto Max settings — so your therapy stays effective and comfortable as your needs evolve over time.

Built-In Heated Humidifier & Heated Tubing

The integrated heated humidifier offers five humidity levels plus an Auto mode that adjusts to your environment, with a pre-heat option to warm the water before bed. The included 6-foot heated tubing helps prevent rainout (condensation in your hose) and maintains an even air temperature through the night, so dry mouth and congestion become a thing of the past. The water chamber removes easily with a push-to-release mechanism for quick daily rinsing.

RESlex Exhalation Relief & Smart Comfort Features

RESlex Exhalation Relief automatically detects your breathing rhythm and lowers pressure during every exhale for a more natural feel — adjustable from level 1 (lowest) to 3 (highest), or off. An adjustable auto ramp (0–60 minutes) eases you into full therapy pressure as you fall asleep, audible leak detection alerts you after 40 seconds of excess leak, and the on-screen Usage Summary scores each session up to 100 points so you always know how your therapy is going.

Everything you need to know about the G3X Auto CPAP Machine.

First Foam-Free PAP in the U.S.

Engineered without polyurethane foam — clean therapeutic air with no off-gassing or degrading materials, and a 5-year warranty.

Works With Any Mask

Compatible with any standard 22mm CPAP mask from any brand — nasal, nasal pillow, or full face. No proprietary lock-in, no adapter needed.

Smart A Adaptive Pressure

Exclusive algorithm fine-tunes your therapy over a rolling 5-session window, adjusting Auto Min and Max to keep treatment effective and comfortable.

Built-In Heated Humidifier & Tube

Integrated humidification with 5 levels plus Auto mode and included heated tubing to reduce dryness and prevent rainout all night.

+ Additional Features
+ Specifications

Ready Support for Sleep Success

Your Lofta therapy continues well beyond the CPAP purchase. We’re here with ongoing information and guidance to keep you on the path to healthy sleep.

Basic Support

Rest easy with Lofta guidance and recommendations.

 
  • On-demand compliance reports ($35)
  • Lofta Respiratory Therapist Team available for support / coaching ($40 for a 20 minute session)
  • Medical forms requiring a physician signature ($35 - $125)
  • 60-Night Mask Exchange
  • Enhanced Return Policy
LoftaCare

Personal support sets you up for success.

$200
  • 1 year of coaching calls
  • 60-Night Cash Back Return
  • 60-Night Unlimited Mask Exchanges
  • 1 Year Supply of Device Filters
  • V-COM Air Flow Reducer
  • Jump Start Coaching (1 wk, 1 mo, 3 mo, 6 mo)
  • 1 additional year of machine warranty Device Product Protection
  • Discounts on future CPAP supply orders
  • Enhanced Return Policy
  • See details
FAQs

Sleep Therapy Simplified

Answers to your common questions about G3X Auto CPAP Machine and tips for getting better sleep every night.

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What is the difference between the G4600 and the G46002?
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Does the React G3 X contain polyurethane foam?
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What therapy modes and pressure range does the G3 X support?
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What masks and tubing are compatible with the G3 X?
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How does the cellular connectivity work, and do I need Wi-Fi?
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What is included in the box?
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Is a prescription required?
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How long is the warranty, and is there a trial period?